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Jonathan Wolfman

Jonathan Wolfman
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Maryland, Northwest of The District,
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January 26
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AUGUST 3, 2011 7:09AM

Do Mammograms Matter?

Rate: 16 Flag

 

     Do mammograms matter? Maybe no.

     Yesterday I shared here what many of us deem terrific news about what the new Affordable Health Care Act covers for women. Today I offer a tad of caution, not about health care reform, but about how comfortable we may become with accepted and standard women's health advice and practice. This news may disconcert.

      The 'British Medical Journal' reports that data-analysis from three separate, paired, long-term European reviews suggest, contrary to researchers' expectations, that screening has no effect on breast cancer deaths. While overall breast cancer mortality has declined a great deal in first-world nations, the study reports that it's very hard to know "how much of the decline is due to early detection, or the efficiency of the health care system".

     Researchers looked at very large 'natural experiments' in three nation-pairs where some had "instituted regular mammography screening significantly earlier than the others, but their health care systems and socioeconomic" profiles were the same. (A 'natural experiment' report is one not based on an arranged scientific inquiry but instead analyses existing data.) The matched-pairs were

          Northern Ireland/The Republic of Ireland;

          The Netherlands/Belgium; and

          Sweden/Norway.

     In all three paired countries, "earlier implementation of screening had no effect on mortality." For instance, in Northern Ireland, screenings were implemented in the early '90s and by '95 three quarters of women were getting mammograms. In the Irish Republic, screening wasn't introduced until 2000 "and it was not until 2008 that 76% of women were screened." And yet from 1989 until to 2006 breast cancer deaths decreased 29% in Northern Ireland and almost as much in the Republic of Ireland. Similar results stemmed from the studies in the other paired countries.

     While the lead researcher, Dr. Philippe Autier, says he was surprised by the results, his team concluded that mamography screening does not work. I'd be interested to see if similar data, collected and studied, say, in a decade (or current data from other nation pairs, should they exist), substantiate or challenge this report.

     There seems no harm, now, in women getting mammograms. Dr. Autier does not suggest there is. The question I have, and one I think you should have, too, is that should another similar study or two evidence the same conclusion, are there better avenues for our health care outlays?

     It's important, no matter how disquieting, to take seriously challenges to conventional wisdom. If (in any area) money can be better allocated than it now is, all families potentially benefit. My hope is that this study is replicated and that additional current data may be analysed. While we tend to take comfort in current thinking and practice, we need to augment public policy on the strength of increasing and solid, confirmed knowledge.

-----

IMPORTANT NOTE:

I want to be sure that you understand that this post is not about, nor is it an outgrowth in any way, of the controversial decision, last fall, of the U.S. government panel's recommendation to raise the age at which most women first ought to have mammograms. The scientists who reported the findings in this post have nothing whatever to do with that panel's work or recommendations.  -JW

   

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I thought this would be of interest. You may find more information about this study at the British Medical Journal, online.

The critical point, I think, is that we always remain open to considering new research, further research, whatever the fall-out. It's the only way we are safe, ultimately.
The last mammogram I had ruined the shape of my breasts and I was cancer-free. That was real swell.
Miguela I'm sorry that happened...and of course, these researchers are not calling for women to rush to stop getting checked out.
But isn't screening early detection? A curious mind I think would ask that question and how the two are defined.

We now have a section in the Boston Sunday Globe called "Ideas," which is basically a summary/rehash of academic studies with starting or unexpected conclusions. Sometimes I note that, over the course of a few months, the studies will contradict each other.
Con as I say, I'd like to see more studies and again, these researchers do not recommend women stop getting mammograms.
I am going to get shot for this but I have not had one in years nor will I get one. My problem is I dont want to know as third time you're out.
HUGGGGGGGGGGG
Linda I get it, but pls take care of you.
Same kind of objections being raised about colonoscopy, I gather. If they were free, OK, but I'm always suspicious of hype when there's money involved - especially when the evidence is still sketchy.

BTW, tried several times to rate - no go.
Nice work Jon! I only get a mammogram every other year since I don't like being exposed to all the radiation. Also I think self-exams work along with the x-ray.
Matt I agree. Tho woman should do all they can to keep safe.
Susie makes sense to me.
Yes. Without mammograms I would have died twice. The small percentage number of those patients whose cancer would not be caught without mammograms is not just a number on paper. That number represents people -- who would othewise be dead. So if it i matters that those people are not dead then mammograms matter.
I had my first and last mammo at age 40. I'm interested in women's health issues and I'll review more info from various sources.

As with most other diagnostic devices, mammograms' purpose is to detect abnormal breast tissue, and screening a patient's health history should also factor into the frequency of mammograms throughout the patient's lifetime. BRAC.
whoop pleased you're ok
Excerpt from www.nbcam.org:
“Many High-Risk Women Refuse Breast MRI” – HealthDay News
For women at high risk of breast cancer, an MRI can help detect malignancies early and is often suggested in addition to annual mammograms. Yet, 42 percent of such women in a new study said no to the test.
I have no opinion because I keep hearing different data. My wife found her cancer in her breast, just in time it seems, so I know women should do manual checks often.
Scan TY! and I'm pleased she's well. And the researchers here have NOT recommended women avoid mammograms. (see above)
The only conclusion here is test more
Good information, timely post.
Right now, mammography is the best thing women have (and the machines have gotten much better in terms of imaging and detection). What Con said is so true; I read so many contradictory things in terms of medical breakthroughs, recommendations, treatment, etc. and not just about mammography. It goes with the territory; any type of study involving lots of people over a long period of time is going to be subject to misinterpretation and multiple conclusions. But until someone actually cures breast cancer or it becomes a chronic condition rather than a death sentence, I think mammography is essential. I just don't understand why, after all these years, all the studies and all the money poured into cancer research, we're not closer to a cure - for all types of cancer, not just breast.
Margaret that we're not closer tio cure is, yes, rather astonishing.
I think mamograms do matter because they are the only tool we have for early detection of breast cancer. My mom died of the disease. I get mamograms because I feel I have to. Thanks for starting the conversation about this important topic.
Another necessary piece of information is whether the same amount of money is spent treating women whose cancers were detected with mammograms (or other technological screenings) as on women whose cancer is not detected until a lump is palpable. If more expensive treatment is required later, or more invasive surgery, a mammogram may be pretty cheap.
A 2006 study published by the Cochrane Collaboration concluded tht for every two thousand women screened for breast cancer with mammography, ten women would be unnecessarily diagnosed with, and in some cases treated for, breast cancer, while one fewer woman would die of breast cancer, but there was no difference in the only statistic that matters, which is all-cause mortality. In other words, the one woman out of two thousand who is spared a death from breast cancer will probably die of something else at about the same time. Remember, breast caner tends to be a disease of old age, a time when the death rate from all causes obviously is rising.

A Norwegian study published last year in the New England Journal of Medicine found that screening for breast cancer with mammography was correlated with a one in two thousand five hundred reduction in the risk of dying of breast cancer, which was not statistically significant. The Norwegian study did not look at all cause mortality.

In plain English, screening for breast cancer with mammography does not save lives.

I must take issue with your contention that there is no harm in women getting mammograms. A diagnosis of cancer can ruin your life. It can bankrupt you, it can make you permanently uninsurable and unemployable. Being treated for cancer can even kill you. Women can and do die from their breast cancer treatment. That's a Hell of price to pay if your "cancer" was a tiny, slow-growing neoplasm which never would have bothered you until you died of something unrelated.
Patrick thanks for adding to this discussion!
I think this is great and important news. It can only open the door to other fields of research.

Rated/Bud
Bud I sure hope it helps.
I'm sure all women would love to stop having those rat-bastard mammo's, but that's not the right tactic. However, I don't think "every woman,e very year" is right either.

I think we need to learn to use it more effectively and in a more financially efficient manner. Yes, money matters because the pot of money is limited; one life saved from breast cancer is not more important than, say, 10 lives from better preventative care for some other disease. Breast cancer gets a ridiculously large pot of money for the mortality/life disruption rate due to astonishingly good PR/disease marketing by Komen and others. Save the ta-tas!

Studies to pinpoint specific populations where mammograms are useful and indicative are the next step. Improving the "next step" diagnostic tools to discern between aggressive forms of cancer and non-cancer or slow-growing cancer are also important. I'd love to see some of those girls walking for the cure running into science eduction instead!!
Thanks, Jonathan, I'll be coming back to read more of the comments to this discussion.
♥R
FusunA it's been informative, this thread!
Jon, one of the problems is that in a poor economy and with governments in financial trouble, research money is disappearing. These types of longitudinal studies with a good random selection of the female population are expensive.

The hope is that this dreadful disease will one day be beaten, perhaps with an immunization shot to give all the cells the correct message. Then such testing will not be necessary. That day can't come soon enough.
Catherine you are so right. r.
I think the future of early breast cancer detection will move toward DNA testing (for genetic predispositions), self-exam, manual exam by doctors with sporadic mammograms. My biggest beef with mammograms is that if you have an iffy mammogram, they AUTOMATICALLY send you for an ultrasound. Why not skip the mammogram and have everyone do an ultrasound instead of a mammogram?? TMI, but my dense-tissue A cups get flagged every single mammogram and I'm sent for an ultrasound, which ends up costing me $$$ even though I have "excellent" insurance. The problem is that because I'm adopted and have no familial medical history, they have to be more proactive than they would ordinarily be. But that's another issue entirely...
Ms V Thanks so much for this perspective.
Because I dislike the mammograms so much, my doctor made a bargain with me. I go and have the procedure every 18 months now, but I can't procrastinate when the time comes. I was happy with escaping for an extra 6 months.
My cousin might be dead if she hadn't had a Mammogram. So.. while they're not perfect, it's currently the best diagnostic tool available. Early detection does make a difference. If I ever have to go through the big C I want to catch it an an early stage, thanks awfully!

I also think we need to insist that better, more accurate diagnostic tools get developed, though.

rated
Mammograms are like medieval torture. But, it's the best we've got, it seems. Every other year now as most insurance won't cover them annually and they are terribly expensive. Due for my annual physical and PAP. More medieval torture in stirrups! Sheesh!
Eve sounds like a good deal to me.
Cathy the gvt should pay for MRIs. Less expensive, in time, to keep women healthy.