Do mammograms matter? Maybe no.
Yesterday I shared here what many of us deem terrific news about what the new Affordable Health Care Act covers for women. Today I offer a tad of caution, not about health care reform, but about how comfortable we may become with accepted and standard women's health advice and practice. This news may disconcert.
The 'British Medical Journal' reports that data-analysis from three separate, paired, long-term European reviews suggest, contrary to researchers' expectations, that screening has no effect on breast cancer deaths. While overall breast cancer mortality has declined a great deal in first-world nations, the study reports that it's very hard to know "how much of the decline is due to early detection, or the efficiency of the health care system".
Researchers looked at very large 'natural experiments' in three nation-pairs where some had "instituted regular mammography screening significantly earlier than the others, but their health care systems and socioeconomic" profiles were the same. (A 'natural experiment' report is one not based on an arranged scientific inquiry but instead analyses existing data.) The matched-pairs were
Northern Ireland/The Republic of Ireland;
The Netherlands/Belgium; and
Sweden/Norway.
In all three paired countries, "earlier implementation of screening had no effect on mortality." For instance, in Northern Ireland, screenings were implemented in the early '90s and by '95 three quarters of women were getting mammograms. In the Irish Republic, screening wasn't introduced until 2000 "and it was not until 2008 that 76% of women were screened." And yet from 1989 until to 2006 breast cancer deaths decreased 29% in Northern Ireland and almost as much in the Republic of Ireland. Similar results stemmed from the studies in the other paired countries.
While the lead researcher, Dr. Philippe Autier, says he was surprised by the results, his team concluded that mamography screening does not work. I'd be interested to see if similar data, collected and studied, say, in a decade (or current data from other nation pairs, should they exist), substantiate or challenge this report.
There seems no harm, now, in women getting mammograms. Dr. Autier does not suggest there is. The question I have, and one I think you should have, too, is that should another similar study or two evidence the same conclusion, are there better avenues for our health care outlays?
It's important, no matter how disquieting, to take seriously challenges to conventional wisdom. If (in any area) money can be better allocated than it now is, all families potentially benefit. My hope is that this study is replicated and that additional current data may be analysed. While we tend to take comfort in current thinking and practice, we need to augment public policy on the strength of increasing and solid, confirmed knowledge.
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IMPORTANT NOTE:
I want to be sure that you understand that this post is not about, nor is it an outgrowth in any way, of the controversial decision, last fall, of the U.S. government panel's recommendation to raise the age at which most women first ought to have mammograms. The scientists who reported the findings in this post have nothing whatever to do with that panel's work or recommendations. -JW


Salon.com
Comments
The critical point, I think, is that we always remain open to considering new research, further research, whatever the fall-out. It's the only way we are safe, ultimately.
We now have a section in the Boston Sunday Globe called "Ideas," which is basically a summary/rehash of academic studies with starting or unexpected conclusions. Sometimes I note that, over the course of a few months, the studies will contradict each other.
HUGGGGGGGGGGG
BTW, tried several times to rate - no go.
As with most other diagnostic devices, mammograms' purpose is to detect abnormal breast tissue, and screening a patient's health history should also factor into the frequency of mammograms throughout the patient's lifetime. BRAC.
“Many High-Risk Women Refuse Breast MRI” – HealthDay News
For women at high risk of breast cancer, an MRI can help detect malignancies early and is often suggested in addition to annual mammograms. Yet, 42 percent of such women in a new study said no to the test.
A Norwegian study published last year in the New England Journal of Medicine found that screening for breast cancer with mammography was correlated with a one in two thousand five hundred reduction in the risk of dying of breast cancer, which was not statistically significant. The Norwegian study did not look at all cause mortality.
In plain English, screening for breast cancer with mammography does not save lives.
I must take issue with your contention that there is no harm in women getting mammograms. A diagnosis of cancer can ruin your life. It can bankrupt you, it can make you permanently uninsurable and unemployable. Being treated for cancer can even kill you. Women can and do die from their breast cancer treatment. That's a Hell of price to pay if your "cancer" was a tiny, slow-growing neoplasm which never would have bothered you until you died of something unrelated.
Rated/Bud
I think we need to learn to use it more effectively and in a more financially efficient manner. Yes, money matters because the pot of money is limited; one life saved from breast cancer is not more important than, say, 10 lives from better preventative care for some other disease. Breast cancer gets a ridiculously large pot of money for the mortality/life disruption rate due to astonishingly good PR/disease marketing by Komen and others. Save the ta-tas!
Studies to pinpoint specific populations where mammograms are useful and indicative are the next step. Improving the "next step" diagnostic tools to discern between aggressive forms of cancer and non-cancer or slow-growing cancer are also important. I'd love to see some of those girls walking for the cure running into science eduction instead!!
♥R
The hope is that this dreadful disease will one day be beaten, perhaps with an immunization shot to give all the cells the correct message. Then such testing will not be necessary. That day can't come soon enough.
I also think we need to insist that better, more accurate diagnostic tools get developed, though.
rated